Multi-Domain Operations (MDO) are emerging as the U.S. military’s answer to China’s system-centric approach to warfare, which seeks to disrupt and paralyze the connective architecture of joint operations. The chapter argues that deterrence in the Indo-Pacific will depend less on platform dominance than on the ability to integrate forces, fuse information, and sustain resilient, allied-enabled command and control through CJADC2 across contested multi-domain environments.